Before assuming his latest role, DeGregorio served as chief integration officer for Exelon during the company's merger with Constellation Energy. In this position, he led the integration of all processes, procedures, systems, staffing and synergies between the two companies. Prior to this, DeGregorio was chief operating officer of the Exelon Transmission Company, responsible for the directing, strategic planning and operational implementation of Exelon's transmission build-out opportunities.
DeGregorio held several critical leadership positions with Exelon Nuclear before joining the Transmission Company, including senior vice president, Operations Support and senior vice president, Mid-Atlantic Operations. DeGregorio has also led several previous integration and cost management initiatives for the company, including the Unicom - PECO merger, the Oyster Creek acquisition and Exelon Way.